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A description of the content follows : New York-based Biophan Technologies, Inc. (BIPH) has developed – and patented – solutions to this serious medical challenge. Biophan develops and markets technologies used to make biomedical devices—such as cardiac pacemakers, surgical and diagnostic tools, safe and compatible with MRI equipment and other sources of powerful magnetism or radio frequency signals. Currently the shares are at 37 cents.

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Russell 2000 545.69 -1.21 VOLUME 03: ISSUE 82 
Trading Alert: Biophan Technologies
If you don’t currently know someone with a pacemaker, cardiac stent or other implanted medical device, you will. That person may even be you.

As the population ages, one thing is irrefutable: more implanted medical devices will be needed. But there’s a big problem. Life-saving Magnetic Resonance Imaging (MRI) procedures which are routinely utilized to quickly detect serious disease, are virtually unavailable to patients with an implanted metal or electronic device.

Problem solved…and more.

New York-based Biophan Technologies (OTCBB: BIPH) has developed—and patented-- solutions to this serious medical challenge. (See Press release attached). Biophan develops and markets technologies used to make biomedical devices—such as cardiac pacemakers, surgical and diagnostic tools, safe and compatible with MRI equipment and other sources of powerful magnetism or radio frequency signals.

Accumulation of the company’s shares at these levels by risk oriented investors is recommended for significant gains over the next 12 months and beyond.

For the technically adept, the above chart shows a 50% price retracement (shares currently 37 cents) following Biophan’s November 2003 run-up and looks to be forming a continued uptrend with opportunistic entry points. A break above 50 cents would confirm the uptrend. Risk-oriented investors should consider accumulating shares up to the 50-cent level in anticipation of significant gains over the next 12 months. A stop at 25 cents would likely be prudent, but perhaps for only half of a position. This stock is volatile.

On November 4th 2003, when BIPH announced its collaboration with Boston Scientific (see below). As a result, the  stock traded over 8 million shares and the price rose from 20 cents to north of 40 cents that day-- in excess of a 100-percent return. This company’s progress is obviously news driven and there are likely significant developments to come, making the shares attractive for both short-term traders and long-term investors.

Biophan bullet points:

  • 12 month trading range of 10 cents to $1.15
  • Shares outstanding 46 million. Float 33 million. 
  • Market cap $17 million.
  • Biophan’s proprietary, patented products include coatings, filters and photonics that significantly minimize the problems experienced to date between MRI electromagnetic fields and interventional as well as implanted devices.
  • Pacemaker market $4 billion plus and growing
  • Medical device—stents, wires, clips, etc, market: $3 billion plus and growing.
  • Exclusive licenses for 3 US issued patents from Johns Hopkins University. Fifty-five-plus further patents pending.
  • Corporate mandate to continue the construction of a significant, revenue-generating portfolio of patented biotechnology intellectual properties.
The potential for the company’s products to herald significant therapeutic medical advancement is unusually compelling.

Given the strong annual growth of both the medical device market and the biotechnology sector, Biophan’s patented, implanted device coating technology should be of extreme interest to risk-oriented investors. As should the company’s business focus to develop and acquire more cutting edge intellectual biotechnology property to enhance revenues through licensing and joint venture deals.

Why Biophan matters to patients and investors:

An MRI is….

MRI uses magnetism to create the images. Unlike regular x-rays or CT scanning, it does not use x-rays or any other type of radiation. An MRI machine uses a very large magnet to create a powerful magnetic field that is used in conjunction with radio waves. The magnetic field and the radio waves stimulate atoms to give off tiny radio signals. The length of time for which these response signals are emitted after an atom is stimulated varies depending upon the body tissue being examined; different types of body tissue emit signals that vary in length. A computer analyzes the different signal lengths and generates cross-sectional images of the body tissues.
Amazing, frankly.

Who shouldn’t—or can’t-- have an MRI?

The magnetic field inside the machinery is so powerful that it can erase credit cards in your wallet, send a metal object flying, or interfere with the workings of an item such as a pacemaker. So some people are not candidates for MRI scans because of metallic implants in their body, such as a pacemaker, any implanted surgical clip, an artificial joint, a metal plate or screw, or a contraceptive diaphragm as in an intrauterine device (IUD). 

Today, many devices (such as pacemakers and surgical devices) are not used with MRI due to safety concerns involved with the MRI environment, including heating of devices and metal wire leads, which can cause tissue damage. 

Number one with a (coated) bullet.

The MRI/medical device initiative alone would likely be enough for most companies. Not Biophan. This small—for now—biotech concerns has big plans.

In early November 2003, Biophan struck a joint development deal with behemoth Boston Scientific (NYSE: BSX) to make MRI-friendly devices as well as explore licensing agreements. Although details of the deal weren’t given, even a modest success in this area would mean that MRI’s could be utilized on many patients who, due to implanted metal and electronic devices, have been, to date, unable to benefit from imaging technology.

Discussions with other major medical device companies are ongoing.

We believe that success in this endeavor will help millions of current and future patients. Extrapolate that to other cutting edge biotech products and technologies and Biophan’s potential is apparent.

If you own it, they will come.

Patents are the currency of business-- particularly technology and biotechnology. As Biophan’s intellectual property portfolio grows, potential licensees will either seek out—or be sought out by—the company to utilize its patented technology. As well, Biophan offers turnkey solutions to customers, including major medical device companies, providing products and R&D backed up by its world-class biotech personnel.

Investors need only look at the recent growth of the coated cardiac stent market to get some understanding of the potential application for Biophan’s products. Companies such as Guidant (NYSE: GDT), Medtronic (NYSE: MDT) and Angiotech (NASDAQ: ANPI) have enjoyed explosive growth as that complimentary therapy found itself at the forefront of both medical and investor interest. 

Making therapies better and safer is, as Biophan represents, just as important and profitable as the original discovery itself.

Below is the complete text of Biophan's news release today for your review. We will continue to follow BIPH’s progress.
 

News Release

Investor Relations Contact: 
Racquel Rivera, Vice President 
Trilogy Capital Partners, Inc. 
800.330.6540 
racquel@trilogy-capital.com

Biophan Technologies Announces 2004 Strategic Initiatives
________________________

Objectives Call for Further Innovation, Market Expansion and Significant Growth

Rochester, NY, December 19, 2003—Biophan Technologies, Inc. (OTC BB: BIPH), an innovator, developer, and marketer of advanced biomedical technology, today announced its Strategic Initiatives for 2004.  The announcement was made by Michael Weiner, Biophan’s CEO. 

Mr. Weiner stated, “With the year drawing to a close and Biophan’s strategic plan being executed, the company is announcing it strategic initiatives for 2004.” 

During 2003 the Company introduced the following:

Strategic Initiative 1—Acquisition of Intellectual Assets:

Biophan’s leadership position in its market segment is highly dependent upon continued development and acquisition of intellectual property.  With three United States patents under license and more than 50 patents pending, the Company is aggressively pursuing internal research and development projects, as well as sourcing leading-edge providers of related technologies.

Intellectual property, such as technology solutions and patents, may be developed internally, through joint ventures, or purchased.  To ensure the continuing value of their intellectual assets, Biophan will aggressively defend its licenses, both domestically and abroad.

Strategic Initiative 2—Market Expansion:

Biophan currently enjoys a leadership position in developing technologies that make implanted medical devices, such as heart pacemakers, safe for use with MRI and other diagnostic imaging tools.  Biophan has also developed technologies that allow for the use of interventional MRI, without the heating problems that can cause tissue damage or imaging problems that obscure the outcome of the procedures. 

Based on discussions underway with several biomedical device manufacturers, both in the U.S. and overseas, Biophan plans to expand the use of the technologies it has developed to make a wider range of devices compatible with MRI.  These technologies reduce radio frequency interference, heating, and induced voltages.  In 2004, the Company will explore opportunities for these technologies in the prosthetic and surgical tool markets, where the lack of MRI compatibility negatively impacts investigational and diagnostic procedures.  Discussions with these device manufacturers indicate a need for, and interest in, solutions to additional problems where Biophan can develop solutions.  Part of Biophan's strategic initiative for 2004 will include expanding its technology offerings to the companies with which it is already in discussions, or working with.  The initiative in contrast agents is the first entry into the pharmaceutical arena. 

Biophan’s Photonic MRI Microcoil (PMM) is one example of the Company’s expanded technology.  Recent studies indicate up to 85% of heart attacks and strokes may be caused by vulnerable plaque which may result in thrombosis, and is not easily detected by other methods.  Biophan’s technologies will pinpoint specific sites where therapies can address the problem.  By inserting the PMM directly into a blood vessel, MRI can provide a detailed look at vulnerable plaque without injury-causing heating or image degradation.

Another example of Biophan expanding on the use of existing, licensed technology is NanoView. NanoView utilizes nanomagnetic particles, a specific type of nanotechnology,  as contrast agents that preferentially bind to tissues of diagnostic interest, creating improved detail and contrast in MRI diagnostic image processes.  NanoView improves performance in terms of signal intensity and the use of multiple markers, which broadens the applications of MRI imaging.

Strategic Initiative 3—Strategic Partnerships:

Leveraging these relationships is vital to Biophan’s mission.  By exploiting its established relationships, such as the recently announced joint development agreement with Boston Scientific, Biophan not only creates ready sales channels but the Company also establishes leverage that has far-reaching impact throughout its market and the investor community.

Biophan has entered into Non-Disclosure Agreements with the major manufacturers of implanted biomedical and related devices.  Discussions underway with these companies include strategic partnerships that may include, joint developments, original equipment manufacturing arrangements and licensing agreements.
 

Summary

Biophan is positioned to exploit its market momentum to gain additional intellectual assets, expand into adjacent markets, cultivate new strategic alliances and fortify internal management and operations with top quality recruits.  This will help Biophan to achieve revenues, earnings, and shareholder value.

We are enthusiastic about our early successes and the milestones we have achieved to date.  Most importantly, Biophan looks forward to substantial growth in revenues, earnings and, ultimately, in shareholder value.

The company is actively meeting with institutional investors in the financial community and encourages all prospective investors to review the Company information on its corporate website: www.biophan.com
 

About Biophan Technologies, Inc.

Biophan Technologies develops and markets cutting-edge technologies used to make biomedical devices—such as cardiac pacemakers, surgical and diagnostic tool—safe and compatible with magnetic resonance imaging (MRI) equipment and other sources of powerful magnetism or radio frequency signals.  Committed to growth through innovation and developmental leadership, Biophan’s management holds exclusive licenses for three issued U.S. patents and has filed 51 related patents that will help establish Biophan products as the standard of care in each of their markets.  For more information, please visit www.biophan.com.

Cautionary Statement Regarding Forward-Looking Statements

Certain statements included in this press release may constitute forward-looking statements.  Actual results could differ materially from such statements expressed or implied herein as a result of a variety of factors including, but not limited to: the development of Biophan's MRI technologies; the approval of Biophan's patent applications; the successful implementation of Biophan's research and development programs; the acceptance by the market of Biophan's products; competition and the timing of projects and trends in future operating performance, as well as other factors expressed from time to time in Biophan's periodic filings with the Securities and Exchange Commission (the "SEC").  As a result, this press release should be read in conjunction with Biophan's periodic filings with the SEC.  The forward-looking statements contained herein are made only as of the date of this press release, and Biophan undertakes no obligation to publicly update such forward-looking statements to reflect subsequent events or circumstances.

Contact:

Investor Relations:
Trilogy Capital Partners, Inc.
Racquel Rivera, 800-330-6540
racquel@trilogy-capital.com
or
Press Interviews:
Biophan Technologies, Inc.
Michael Weiner, 585-214-2441


 
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